Mepron (atovaquone)

Mepron chemical name: (atovaquone)

Uses:

• Mepron (Atovaquone) is an antiprotozoal medication used for the treatment and prevention of various protozoal infections, including:
  • Malaria caused by Plasmodium falciparum and Plasmodium vivax
  • Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii in patients who are immunocompromised, such as those with HIV/AIDS.
  • Toxoplasmosis caused by Toxoplasma gondii.

Mechanism of Action:

• Atovaquone works by inhibiting the mitochondrial electron transport chain in protozoa, disrupting their energy metabolism and leading to their death.

Dosage:

• The dosage of Mepron prescribed will depend on the specific infection being treated, the patient’s age, weight, and overall health condition.
• Mepron is usually taken orally as a suspension and may be taken with food to improve absorption.
• Dosage regimens for malaria prophylaxis, treatment of acute malaria, and treatment of PCP or toxoplasmosis vary and should be determined by a healthcare professional.

Side Effects:

• Common side effects of Mepron may include nausea, vomiting, diarrhea, stomach pain, headache, and rash.
• Other potential side effects include liver enzyme abnormalities, yellowing of the skin or eyes (jaundice), and allergic reactions.
• Mepron may also interact with other medications, including rifamycins, anticonvulsants, and antiretroviral drugs, so it’s essential to inform the doctor of all medications being taken.